Variance means nothing without expected value. So start here: https://en.wikipedia.org/wiki/Expected_valueI was using https://en.wikipedia.org/wiki/Variance as the basis for my theory.
In this case, you could look at what level of firepower you need to direct towards an Escher leader or champion in order to attain a 1/12 chance of taking them out. You will realize that, by using maximum firepower with a plasma weapon, you are essentially giving your opponent a free shot at you with a pretty decent weapon. A shot that they neither need to use an activation, nor make an ammo check, for.